rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1991-12-31
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pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M81959,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S66451,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S66454,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S78944,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S78945,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S78946,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S78947,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S78948,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S78949,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S78950,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/X59548,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/X59549
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pubmed:abstractText |
CHox E is a novel chicken homeogene that belongs to the H2.0 family of homeodomains. Its homeobox sequence is interrupted by an intron between amino acids 44 and 45. Expression of CHox E during embryogenesis is localized to the central nervous system. The anterior boundary of CHox E expression can initially be localized to rhombomere number 1, later in development this boundary reaches up to the rhombencephalic isthmus. CHox E expression in the spinal cord localizes dorso-ventrally to the dorsal half of the basal plate. CHox E expression is always restricted to the proliferating region, the ventricular zone. As the ventricular zone becomes restricted laterally, so does the CHox E expressing region. Once this region of the ventricular zone ceases to exist, CHox E specific transcripts become undetectable. The site and time of CHox E expression suggest a very early function in the differentiation of the cells derived from that region of the ventricular zone.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0925-4773
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:geneSymbol |
CHox E
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
13-24
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1683253-Amino Acid Sequence,
pubmed-meshheading:1683253-Animals,
pubmed-meshheading:1683253-Base Sequence,
pubmed-meshheading:1683253-Cell Differentiation,
pubmed-meshheading:1683253-Cell Division,
pubmed-meshheading:1683253-Chick Embryo,
pubmed-meshheading:1683253-DNA,
pubmed-meshheading:1683253-Embryonic and Fetal Development,
pubmed-meshheading:1683253-Gene Expression Regulation,
pubmed-meshheading:1683253-Genes, Homeobox,
pubmed-meshheading:1683253-Introns,
pubmed-meshheading:1683253-Molecular Sequence Data,
pubmed-meshheading:1683253-Neurons,
pubmed-meshheading:1683253-Spinal Cord,
pubmed-meshheading:1683253-Transcription, Genetic
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pubmed:year |
1991
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pubmed:articleTitle |
CHox E, a chicken homeogene of the H2.0 type exhibits dorso-ventral restriction in the proliferating region of the spinal cord.
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pubmed:affiliation |
Department of Genetics, Hebrew University, Jerusalem, Israel.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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