rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2006-7-11
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pubmed:abstractText |
Cholesteryl ester transfer protein (CETP) inhibitors (JTT-705 and torcetrapib) are currently in clinical testing, and significantly raise high-density lipoprotein (HDL) cholesterol levels. Low HDL cholesterol is a significant independent predictor of coronary heart disease (CHD) and HDL raising has been associated with coronary heart disease risk reduction, but there is debate about whether CETP inhibition will reduce coronary heart disease risk.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CETP protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol Ester Transfer Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Quinolines,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfhydryl Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/dalcetrapib,
http://linkedlifedata.com/resource/pubmed/chemical/torcetrapib
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0957-9672
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
394-8
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pubmed:dateRevised |
2009-10-8
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pubmed:meshHeading |
pubmed-meshheading:16832162-Animals,
pubmed-meshheading:16832162-Carrier Proteins,
pubmed-meshheading:16832162-Cholesterol Ester Transfer Proteins,
pubmed-meshheading:16832162-Coronary Disease,
pubmed-meshheading:16832162-Glycoproteins,
pubmed-meshheading:16832162-Humans,
pubmed-meshheading:16832162-Lipid Metabolism,
pubmed-meshheading:16832162-Lipoproteins, HDL,
pubmed-meshheading:16832162-Quinolines,
pubmed-meshheading:16832162-Risk,
pubmed-meshheading:16832162-Sulfhydryl Compounds
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pubmed:year |
2006
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pubmed:articleTitle |
Cholesteryl ester transfer protein inhibition, high-density lipoprotein metabolism and heart disease risk reduction.
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pubmed:affiliation |
Cardiovascular Research and Lipid Metabolism Laboratories, Tufts University, Boston, Massachusetts, USA. ernst.schaefer@tufts.edu
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pubmed:publicationType |
Journal Article,
Review
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