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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2006-7-11
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pubmed:abstractText |
Neuromyelitis optica (NMO)-IgG is a specific autoantibody marker for NMO. It binds selectively to aquaporin 4 (AQP4), which is highly concentrated in astrocytic foot processes at the blood-brain barrier and is not restricted to optic nerve and spinal cord. Although it is conventionally believed that the brain is spared, brain imaging abnormalities are not uncommon in patients with NMO.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0003-9942
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
964-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16831965-Adolescent,
pubmed-meshheading:16831965-Adult,
pubmed-meshheading:16831965-Aquaporin 4,
pubmed-meshheading:16831965-Autoantibodies,
pubmed-meshheading:16831965-Cerebral Ventricles,
pubmed-meshheading:16831965-Child, Preschool,
pubmed-meshheading:16831965-Female,
pubmed-meshheading:16831965-Humans,
pubmed-meshheading:16831965-Hypothalamus,
pubmed-meshheading:16831965-Immunoglobulin G,
pubmed-meshheading:16831965-Magnetic Resonance Imaging,
pubmed-meshheading:16831965-Male,
pubmed-meshheading:16831965-Middle Aged,
pubmed-meshheading:16831965-Neuromyelitis Optica,
pubmed-meshheading:16831965-Retrospective Studies
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pubmed:year |
2006
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pubmed:articleTitle |
Neuromyelitis optica brain lesions localized at sites of high aquaporin 4 expression.
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pubmed:affiliation |
Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905-0001, USA. Pittock.sean@mayo.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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