|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2006-7-11
|
|
pubmed:abstractText |
Inflammatory bowel disease (IBD) is characterized by the T-cell excessive activation of intestinal mucosa. Cytotoxic T-lymphocyte associated antigen 4 (CTLA-4) is a negative regulator of T-lymphocyte activation. The aim of the present study is to investigate the association between CTLA-4 promoter -1722 (T/C), -1661 (A/G) polymorphisms and ulcerative colitis (UC) in Han Chinese, in Hubei province of central China.
|
|
pubmed:language |
chi
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0578-1426
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
45
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
478-81
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:16831326-Adult,
pubmed-meshheading:16831326-Alleles,
pubmed-meshheading:16831326-Antigens, CD,
pubmed-meshheading:16831326-Antigens, Differentiation,
pubmed-meshheading:16831326-CTLA-4 Antigen,
pubmed-meshheading:16831326-Case-Control Studies,
pubmed-meshheading:16831326-Colitis, Ulcerative,
pubmed-meshheading:16831326-Female,
pubmed-meshheading:16831326-Gene Frequency,
pubmed-meshheading:16831326-Genotype,
pubmed-meshheading:16831326-Humans,
pubmed-meshheading:16831326-Male,
pubmed-meshheading:16831326-Middle Aged,
pubmed-meshheading:16831326-Polymerase Chain Reaction,
pubmed-meshheading:16831326-Polymorphism, Genetic,
pubmed-meshheading:16831326-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:16831326-Promoter Regions, Genetic,
pubmed-meshheading:16831326-T-Lymphocytes, Cytotoxic
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
[Cytotoxic T lymphocyte antigen-4 promoter gene polymorphism is significantly associated with ulcerative colitis].
|
|
pubmed:affiliation |
Department of Internal Medicine, Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.
|
|
pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
|
