Linked Life Data

16828933

Source:http://linkedlifedata.com/resource/pubmed/id/16828933

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2006-11-6
pubmed:abstractText
A series of beta-amino alcohol analogs of sugiol were synthesized in a straightforward manner. The in vitro antiproliferative activities were examined in the human solid tumor cell lines A2780, SW1573 and WiDr. The most potent analogs induced considerably growth inhibition in the range 1.5-6.7 microM. The results showed that beta-amino alcohol analogs are more potent than the parent compound. In addition, the derivatives with secondary amine fragments showed more active than those bearing tertiary amines.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0223-5234
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1327-32
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Synthesis and antiproliferative activity of novel sugiol beta-amino alcohol analogs.
pubmed:affiliation
Instituto Universitario de Bio-Orgánica Antonio González (IUBO-AG), Universidad de La Laguna, C/ Astrofísico Francisco Sánchez 2, La Laguna, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't