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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
23
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pubmed:dateCreated |
1991-12-11
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pubmed:abstractText |
Multidrug resistance in chemotherapy for cancer is characterized by increased genetic expression of P-glycoprotein, which acts as an ATP-dependent drug-efflux pump. To determine whether P-glycoprotein levels are of prognostic value in such cases, we measured these levels immunohistochemically in a retrospective study of sequential tumor samples from 67 children with neuroblastoma.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0028-4793
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
325
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1608-14
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:1682809-Child,
pubmed-meshheading:1682809-Drug Resistance,
pubmed-meshheading:1682809-Genes, myc,
pubmed-meshheading:1682809-Humans,
pubmed-meshheading:1682809-Membrane Glycoproteins,
pubmed-meshheading:1682809-Neoplasm Proteins,
pubmed-meshheading:1682809-Neoplasm Staging,
pubmed-meshheading:1682809-Neuroblastoma,
pubmed-meshheading:1682809-P-Glycoprotein,
pubmed-meshheading:1682809-Prognosis,
pubmed-meshheading:1682809-Retrospective Studies,
pubmed-meshheading:1682809-Treatment Outcome
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pubmed:year |
1991
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pubmed:articleTitle |
P-glycoprotein expression as a predictor of the outcome of therapy for neuroblastoma.
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pubmed:affiliation |
Department of Pediatrics, Hospital for Sick Children, Toronto, ON, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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