Source:http://linkedlifedata.com/resource/pubmed/id/16827617
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
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| pubmed:dateCreated |
2006-7-10
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| pubmed:abstractText |
In the sub-Saharan African meningitis belt there is a region of hyperendemic and epidemic meningitis stretching from Senegal to Ethiopia. The public health approaches to meningitis epidemics, including those related to vaccine use, have assumed that Neisseria meningitidis serogroup A will cause the most disease. During 2001 and 2002, the first large-scale epidemics of serogroup W135 meningitis in sub-Saharan Africa were reported from Burkina Faso. The occurrence of N. meningitidis W135 epidemics has led to a host of new issues, including the need for improved laboratory diagnostics for identifying serogroups during epidemics, an affordable supply of serogroup W135-containing polysaccharide vaccine for epidemic control where needed, and re-evaluating the long-term strategy of developing a monovalent A conjugate vaccine for the region. This review summarizes the existing data on N. meningitidis W135 epidemiology, immunology and vaccines as they relate to meningitis in sub-Saharan Africa.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Jun
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| pubmed:issn |
1744-8395
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
5
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
319-36
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| pubmed:dateRevised |
2007-11-15
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| pubmed:meshHeading |
pubmed-meshheading:16827617-Adolescent,
pubmed-meshheading:16827617-Adult,
pubmed-meshheading:16827617-Africa South of the Sahara,
pubmed-meshheading:16827617-Carrier State,
pubmed-meshheading:16827617-Child,
pubmed-meshheading:16827617-Child, Preschool,
pubmed-meshheading:16827617-Clinical Trials as Topic,
pubmed-meshheading:16827617-Communicable Diseases, Emerging,
pubmed-meshheading:16827617-Disease Outbreaks,
pubmed-meshheading:16827617-Humans,
pubmed-meshheading:16827617-Infant,
pubmed-meshheading:16827617-Meningitis, Meningococcal,
pubmed-meshheading:16827617-Meningococcal Vaccines,
pubmed-meshheading:16827617-Neisseria meningitidis, Serogroup W-135,
pubmed-meshheading:16827617-Seroepidemiologic Studies,
pubmed-meshheading:16827617-Serotyping,
pubmed-meshheading:16827617-Vaccination
|
| pubmed:year |
2006
|
| pubmed:articleTitle |
Meningococcal serogroup W135 in the African meningitis belt: epidemiology, immunity and vaccines.
|
| pubmed:affiliation |
Agence de Médecine Préventive, 25 du Dr Roux, 75724 Paris cedex 15, France. jmueller@aamp.org
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| pubmed:publicationType |
Journal Article,
Review
|