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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8778
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pubmed:dateCreated |
1991-12-19
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pubmed:abstractText |
The value of programmes to control pulmonary tuberculosis in developing countries remains the subject of debate. We have examined the cost-effectiveness of chemotherapy programmes for the control of pulmonary sputum-smear-positive tuberculosis in Malawi, Mozambique, and Tanzania. Effective cure rates of 86-90% were achieved with short-course chemotherapy and of 60-66% with standard chemotherapy. The average incremental costs per year of life saved were US $1.7-2.1 for short-course chemotherapy with hospital admission, $2.4-3.4 for standard chemotherapy with hospital admission, $0.9-1.1 for ambulatory short-course chemotherapy, and $0.9-1.3 for ambulatory standard chemotherapy. Chemotherapy for smear-positive tuberculosis is thus cheaper than other cost-effective health interventions such as immunisation against measles and oral rehydration therapy. Because the greatest benefit of chemotherapy is reduced transmission of the bacillus, treating HIV-seropositive, tuberculosis smear-positive patients would be only slightly less cost-effective than treating HIV-seronegative, tuberculosis-smear-positive patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
23
|
pubmed:volume |
338
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1305-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1682693-Ambulatory Care,
pubmed-meshheading:1682693-Antitubercular Agents,
pubmed-meshheading:1682693-Clinical Protocols,
pubmed-meshheading:1682693-HIV Seropositivity,
pubmed-meshheading:1682693-Humans,
pubmed-meshheading:1682693-Malawi,
pubmed-meshheading:1682693-Mozambique,
pubmed-meshheading:1682693-Sputum,
pubmed-meshheading:1682693-Tanzania,
pubmed-meshheading:1682693-Tuberculosis, Pulmonary
|
pubmed:year |
1991
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pubmed:articleTitle |
Cost effectiveness of chemotherapy for pulmonary tuberculosis in three sub-Saharan African countries.
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pubmed:affiliation |
Center for Population Studies, Harvard University, Cambridge, Massachusetts 02138.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|