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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8776
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pubmed:dateCreated |
1991-12-9
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pubmed:abstractText |
Although lymphoid tissue is absent in normal gastric mucosa, primary lymphomas arise in the stomach and most of these recapitulate the features of mucosa-associated lymphoid tissue (MALT). Gastric lymphoid tissue is known to be acquired in response to local infection by Helicobacter pylori, and we have confirmed this in 450 patients with H pylori-associated gastritis of whom 125 showed mucosal lymphoid follicles. In 8 patients, B lymphocytes infiltrated epithelium, which is a feature characteristic of MALT. We also examined 110 cases of gastric MALT lymphoma and found H pylori infection in 101 of these (92%). We conclude that gastric MALT is acquired in H pylori infection and that this provides the necessary background in which MALT lymphoma might develop.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
9
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pubmed:volume |
338
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1175-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1682595-Gastric Mucosa,
pubmed-meshheading:1682595-Gastritis,
pubmed-meshheading:1682595-Helicobacter Infections,
pubmed-meshheading:1682595-Helicobacter pylori,
pubmed-meshheading:1682595-Humans,
pubmed-meshheading:1682595-Lymphoma, B-Cell,
pubmed-meshheading:1682595-Retrospective Studies,
pubmed-meshheading:1682595-Stomach Neoplasms
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pubmed:year |
1991
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pubmed:articleTitle |
Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma.
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pubmed:affiliation |
Department of Histopathology, University College and Middlesex School of Medicine, London, UK.
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pubmed:publicationType |
Journal Article
|