|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2007-2-5
|
|
pubmed:abstractText |
Myocardial no-reflow, has been associated with alterations in endothelial junctions, which is regulated in part by endothelial dysfunction. Carvedilol is an alpha1 and nonselective beta-adrenergic receptor antagonist with antioxidative properties known to protect endothelial function. Therefore, we hypothesized that carvedilol might also have protective effects on myocardial no-reflow and endothelial junctions.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1874-1754
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
14
|
|
pubmed:volume |
115
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
334-41
|
|
pubmed:meshHeading |
pubmed-meshheading:16824628-Adrenergic alpha-Antagonists,
pubmed-meshheading:16824628-Animals,
pubmed-meshheading:16824628-Blood Flow Velocity,
pubmed-meshheading:16824628-Blotting, Western,
pubmed-meshheading:16824628-Carbazoles,
pubmed-meshheading:16824628-Chemoprevention,
pubmed-meshheading:16824628-Coronary Circulation,
pubmed-meshheading:16824628-Disease Models, Animal,
pubmed-meshheading:16824628-Echocardiography,
pubmed-meshheading:16824628-Endothelium, Vascular,
pubmed-meshheading:16824628-Female,
pubmed-meshheading:16824628-Immunohistochemistry,
pubmed-meshheading:16824628-Ligation,
pubmed-meshheading:16824628-Male,
pubmed-meshheading:16824628-Myocardial Infarction,
pubmed-meshheading:16824628-Myocardial Reperfusion,
pubmed-meshheading:16824628-Myocardial Reperfusion Injury,
pubmed-meshheading:16824628-Propanolamines,
pubmed-meshheading:16824628-Random Allocation,
pubmed-meshheading:16824628-Reference Values,
pubmed-meshheading:16824628-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16824628-Swine
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Carvedilol preserves endothelial junctions and reduces myocardial no-reflow after acute myocardial infarction and reperfusion.
|
|
pubmed:affiliation |
Fu-Wai Heart Hospital, Chinese Academy of Medical Sciences, Beijing, PR China.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
