Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-10-10
pubmed:abstractText
Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrate phyla. This has led to a renewed interest regarding homologies between blood cell types and their developmental origin among different animals. One way to address these areas of inquiry is to shed more light on the biology of blood cells in extant invertebrate taxa that have branched off the bilaterian tree in between insects and vertebrates. This review attempts, in a broadly comparative manner, to update the existing literature that deals with early blood cell development. I begin by providing a brief survey of the different types of blood cell lineages among metazoa. There is now good reason to believe that, in vertebrates and invertebrates alike, blood cell lineages diverge from a common type of progenitor cell, the hemocytoblast. I give a synopsis of the origin and determination of the hematocytoblast, beginning with a look at the hematopoietic organs that house hemocytoblasts in adult animals, followed by a more detailed overview of the embryonic development of the hematopoietic organ. Finally, I compare the process of blood lineage diversification in vertebrates and Drosophila.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1081-0706
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
677-712
pubmed:dateRevised
2007-12-3
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Blood cells and blood cell development in the animal kingdom.
pubmed:affiliation
Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, California 90095, USA. volkerh@mcdb.ucla.edu
pubmed:publicationType
Journal Article, Review, Research Support, N.I.H., Extramural