Linked Life Data

16821216

Source:http://linkedlifedata.com/resource/pubmed/id/16821216

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2006-7-5
pubmed:abstractText
A pheochromocytoma is a neoplasm composed of cells which synthesize and release catecholamines. These tumors produce the hypertension which can be cured with surgical excision of the lesion. The pathological picture of pheochromocytomas is varied and nothing but the presence of metastases can determine aggressiveness of this neoplasm. Current studies try to look for other biological markers which can separate malignant tumors before they metastasize. It allows to target with more effective therapy. Many studies analyze details of microscopic features of these tumors, immunohistochemical markers and molecular disorders. It seems that the most important factor in estimation of aggressiveness of pheochromocytomas is PASS scale. The detection of high expression of telomerase and hTERT and high proliferative activity, measured by immunohistochemistry with the MIB-1 antibody supports most strongly biological malignancy of pheochromocytoma.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0423-104X
pubmed:author
pubmed:issnType
Print
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
946-51
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Markers of malignancy in pheochromocytomas].
pubmed:affiliation
Medical University of Lodz, Poland.
pubmed:publicationType
Journal Article, English Abstract, Review