Linked Life Data

16820244

Source:http://linkedlifedata.com/resource/pubmed/id/16820244

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2006-9-18
pubmed:abstractText
The role of positive darwinian selection in evolution at the molecular level has been keenly debated for many years, with little resolution. However, a recent increase in DNA sequence data and the development of new methods of analysis have finally made this question tractable. Here, I review the current state-of-play of the field. Initial estimates in Drosophila suggest that approximately 50% of all amino acid substitutions, and a substantial fraction of substitutions in non-coding DNA, have been fixed as a consequence of adaptive evolution. Estimates in microorganisms are even higher. By contrast, there is little evidence of widespread adaptive evolution in our own species.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0169-5347
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
569-75
pubmed:dateRevised
2011-5-3
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
The genomic rate of adaptive evolution.
pubmed:affiliation
National Evolutionary Synthesis Center, Durham, NC 27705, USA. a.c.eyre-walker@sussex.ac.uk
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't