Linked Life Data

16817614

Source:http://linkedlifedata.com/resource/pubmed/id/16817614

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-7-4
pubmed:abstractText
Modeling abnormal depolarization of the ventricles may provide a means to localize sites of arrhythmia foci from the body surface recordings. In this paper, we present a single moving dipole (SMD) model of the ventricular depolarization. The model can reproduce characteristic QRS patterns comparable to the clinical recordings when it is located in an inhomogeneous torso model. Our approach involves estimating a series of dipole moments based on vectocardiograms and estimating trajectories based on the three-dimensional isochrone of the ventricular activation. The patterns of body surface potential isochrones are consistent with those from previous studies. The SMD model was also used to simulate posterior wall infarction, which matched the criteria for this diagnosis. In conclusion, our SMD model provided a base for further ventricular depolarization studies and this equivalent dipole approach might be useful in investigating ventricular arrhythmias and their site of origin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0067-8856
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
237-42
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
A single moving dipole model of ventricular depolarization.
pubmed:affiliation
Weldon School of Biomedical Engineering, Purdue University, IN, USA.
pubmed:publicationType
Journal Article