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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2006-7-3
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pubmed:abstractText |
It has been known that phosphate homeostasis is mainly regulated by parathyroid hormone and vitamin D. Fibroblast growth factor 23 (FGF23) has been identified as a novel factor that regulates vitamin D and phosphate metabolism. Genetic defect of FGF23 in mice revealed not only abnormal vitamin D and phosphate metabolism, but also premature aging-like phenotype that is quite similar to Klotho mice. Regulation of vitamin D and phosphate metabolism is closely related to aging processes as well as bone and mineral metabolism.
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pubmed:language |
jpn
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0917-5857
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1137-42
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pubmed:dateRevised |
2007-2-12
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pubmed:meshHeading |
pubmed-meshheading:16816473-Aging,
pubmed-meshheading:16816473-Aging, Premature,
pubmed-meshheading:16816473-Animals,
pubmed-meshheading:16816473-Bone and Bones,
pubmed-meshheading:16816473-Fibroblast Growth Factors,
pubmed-meshheading:16816473-Forkhead Transcription Factors,
pubmed-meshheading:16816473-Glucuronidase,
pubmed-meshheading:16816473-Humans,
pubmed-meshheading:16816473-Insulin-Like Growth Factor I,
pubmed-meshheading:16816473-Mice,
pubmed-meshheading:16816473-Phosphates,
pubmed-meshheading:16816473-Phosphorus, Dietary,
pubmed-meshheading:16816473-Signal Transduction,
pubmed-meshheading:16816473-Vitamin D
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pubmed:year |
2006
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pubmed:articleTitle |
[Vitamin D and phosphate metabolism; relationship with aging-regulating gene].
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pubmed:affiliation |
University of Tokushima Graduate School, Institute of Health Biosciences, Department of Clinical Nutrition.
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pubmed:publicationType |
Journal Article,
English Abstract,
Review
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