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rdf:type |
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lifeskim:mentions |
umls-concept:C0023676,
umls-concept:C0028754,
umls-concept:C0060095,
umls-concept:C0392747,
umls-concept:C0681850,
umls-concept:C0871261,
umls-concept:C1550501,
umls-concept:C1554963,
umls-concept:C1704632,
umls-concept:C1706203,
umls-concept:C1706817,
umls-concept:C1882417,
umls-concept:C2349001,
umls-concept:C2697811,
umls-concept:C2911692
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pubmed:issue |
4
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pubmed:dateCreated |
2006-8-4
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pubmed:abstractText |
It has been found that the expression of fatty acid binding protein 2 (FABP2) mRNA is under dietary control. A G-to-A transition at codon 54 of FABP2 results in an amino acid substitution (from Ala 54 to Thr 54). This polymorphism was associated with high insulin resistance and high fasting insulin concentrations. The aim of our study was to investigate the influence of Thr54 polymorphism in the FABP2 protein on the response to a lifestyle modification (Mediterranean hypocaloric diet and exercise) in obese patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-6807
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2006 S. Karger AG, Basel.
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
354-60
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pubmed:meshHeading |
pubmed-meshheading:16809903-Adipose Tissue,
pubmed-meshheading:16809903-Blood Glucose,
pubmed-meshheading:16809903-Blood Pressure,
pubmed-meshheading:16809903-Cholesterol, LDL,
pubmed-meshheading:16809903-Diet, Reducing,
pubmed-meshheading:16809903-Exercise,
pubmed-meshheading:16809903-Fatty Acid-Binding Proteins,
pubmed-meshheading:16809903-Female,
pubmed-meshheading:16809903-Genotype,
pubmed-meshheading:16809903-Humans,
pubmed-meshheading:16809903-Leptin,
pubmed-meshheading:16809903-Life Style,
pubmed-meshheading:16809903-Male,
pubmed-meshheading:16809903-Middle Aged,
pubmed-meshheading:16809903-Obesity,
pubmed-meshheading:16809903-Oxygen Consumption,
pubmed-meshheading:16809903-Polymorphism, Genetic,
pubmed-meshheading:16809903-Prospective Studies,
pubmed-meshheading:16809903-RNA, Messenger,
pubmed-meshheading:16809903-Treatment Outcome,
pubmed-meshheading:16809903-Weight Loss
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pubmed:year |
2006
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pubmed:articleTitle |
Influence of ALA54THR polymorphism of fatty acid binding protein 2 on lifestyle modification response in obese subjects.
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pubmed:affiliation |
Institute of Endocrinology and Nutrition, Medical School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain. dadluis@yahoo.es
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pubmed:publicationType |
Journal Article
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