16807527

Source:http://linkedlifedata.com/resource/pubmed/id/16807527

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0026336, umls-concept:C0037083, umls-concept:C0040690, umls-concept:C1112768, umls-concept:C1314939, umls-concept:C1710082
pubmed:dateCreated	2006-6-29
pubmed:abstractText	To develop a new animal model of anterior subcapsular cataract formation by topical application of alkali to the eye and to examine the role of Transforming growth factorbeta/Smad3 (TGFbeta/Smad3) signaling in the formation of this cataract model.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9605351
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Actins, http://linkedlifedata.com/resource/pubmed/chemical/Alkalies, http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factor 2, http://linkedlifedata.com/resource/pubmed/chemical/Proliferating Cell Nuclear Antigen, http://linkedlifedata.com/resource/pubmed/chemical/Smad3 Protein, http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors, http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta, http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta2, http://linkedlifedata.com/resource/pubmed/chemical/snail family transcription factors
pubmed:status	MEDLINE
pubmed:issn	1090-0535
pubmed:author	pubmed-author:FlandersKathleen CKC, pubmed-author:OhnishiYoshitakaY, pubmed-author:OkadaYukaY, pubmed-author:OoshimaAkiraA, pubmed-author:SaikaShizuyaS, pubmed-author:ShiraiKumiK, pubmed-author:TanakaTakeshiT
pubmed:issnType	Electronic
pubmed:volume	12
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	681-91
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:16807527-Actins, pubmed-meshheading:16807527-Alkalies, pubmed-meshheading:16807527-Animals, pubmed-meshheading:16807527-Aqueous Humor, pubmed-meshheading:16807527-Burns, Chemical, pubmed-meshheading:16807527-Cataract, pubmed-meshheading:16807527-Cell Death, pubmed-meshheading:16807527-Cell Proliferation, pubmed-meshheading:16807527-Disease Models, Animal, pubmed-meshheading:16807527-Epithelium, pubmed-meshheading:16807527-Fibroblast Growth Factor 2, pubmed-meshheading:16807527-Fibroblasts, pubmed-meshheading:16807527-Lens, Crystalline, pubmed-meshheading:16807527-Male, pubmed-meshheading:16807527-Mesoderm, pubmed-meshheading:16807527-Mice, pubmed-meshheading:16807527-Mice, Knockout, pubmed-meshheading:16807527-Muscle, Smooth, pubmed-meshheading:16807527-Myocytes, Smooth Muscle, pubmed-meshheading:16807527-Proliferating Cell Nuclear Antigen, pubmed-meshheading:16807527-Rats, pubmed-meshheading:16807527-Rats, Wistar, pubmed-meshheading:16807527-Signal Transduction, pubmed-meshheading:16807527-Smad3 Protein, pubmed-meshheading:16807527-Tissue Distribution, pubmed-meshheading:16807527-Transcription Factors, pubmed-meshheading:16807527-Transforming Growth Factor beta, pubmed-meshheading:16807527-Transforming Growth Factor beta2
pubmed:year	2006
pubmed:articleTitle	A new model of anterior subcapsular cataract: involvement of TGFbeta/Smad signaling.
pubmed:affiliation	Department of Ophthalmology, Wakayama Medical University, Kimiidera, Wakayama, Japan. shirai@wakayama-med.ac.jp
pubmed:publicationType	Journal Article