rdf:type |
|
lifeskim:mentions |
umls-concept:C0018787,
umls-concept:C0018790,
umls-concept:C0024109,
umls-concept:C0033487,
umls-concept:C0178602,
umls-concept:C0205081,
umls-concept:C0205494,
umls-concept:C0332161,
umls-concept:C0439590,
umls-concept:C0442087,
umls-concept:C1269765,
umls-concept:C1274040,
umls-concept:C1280551,
umls-concept:C1637379,
umls-concept:C2350385
|
pubmed:issue |
2
|
pubmed:dateCreated |
2006-8-14
|
pubmed:abstractText |
Propofol has been shown to protect against neuronal damage induced by brain ischaemia in small animal models. We reported previously that mild hypothermia (33 degrees C) in combination with extracorporeal lung and heart assist (ECLHA) improved the neurological outcome in dogs with cardiac arrest (CA) of 15 min induced during normothermia. In the present study, we investigated the neuroprotective effect of propofol infusion under mild hypothermia with ECLHA in this model.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0300-9572
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
70
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
275-84
|
pubmed:dateRevised |
2009-8-25
|
pubmed:meshHeading |
pubmed-meshheading:16806640-Anesthetics, Intravenous,
pubmed-meshheading:16806640-Animals,
pubmed-meshheading:16806640-Brain Diseases,
pubmed-meshheading:16806640-Dogs,
pubmed-meshheading:16806640-Female,
pubmed-meshheading:16806640-Heart Arrest,
pubmed-meshheading:16806640-Heart-Assist Devices,
pubmed-meshheading:16806640-Hypothermia, Induced,
pubmed-meshheading:16806640-Midazolam,
pubmed-meshheading:16806640-Propofol,
pubmed-meshheading:16806640-Respiration, Artificial,
pubmed-meshheading:16806640-Time Factors
|
pubmed:year |
2006
|
pubmed:articleTitle |
A moderate dose of propofol and rapidly induced mild hypothermia with extracorporeal lung and heart assist (ECLHA) improve the neurological outcome after prolonged cardiac arrest in dogs.
|
pubmed:affiliation |
Department of Anesthesiology, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, and Kumamoto Rehabiliation Hospital, Japan. ichikei1234@yahoo.co.jp
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|