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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2006-8-30
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pubmed:abstractText |
Adenomas can develop in the pouch after colectomy with ileal pouch-anal anastomosis (IPAA) in patients with familial adenomatous polyposis (FAP). Glutathione S-transferases (GSTs) have a protective role in carcinogenesis. GST activity is much higher in the ileum than in the colon. The present study examined the hypothesis that the protective capacity of GSTs may be lowered as a result of colonic metaplasia of the ileal pouch.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0007-1323
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pubmed:author |
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pubmed:copyrightInfo |
Copyright (c) 2006 British Journal of Surgery Society Ltd.
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pubmed:issnType |
Print
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1108-14
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16804871-Adenomatous Polyposis Coli,
pubmed-meshheading:16804871-Adolescent,
pubmed-meshheading:16804871-Adult,
pubmed-meshheading:16804871-Aged,
pubmed-meshheading:16804871-Biopsy, Needle,
pubmed-meshheading:16804871-Colectomy,
pubmed-meshheading:16804871-Colon,
pubmed-meshheading:16804871-Colonic Pouches,
pubmed-meshheading:16804871-Cysteine,
pubmed-meshheading:16804871-Female,
pubmed-meshheading:16804871-Glutathione,
pubmed-meshheading:16804871-Glutathione Transferase,
pubmed-meshheading:16804871-Humans,
pubmed-meshheading:16804871-Male,
pubmed-meshheading:16804871-Metaplasia,
pubmed-meshheading:16804871-Middle Aged,
pubmed-meshheading:16804871-Proctocolectomy, Restorative
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pubmed:year |
2006
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pubmed:articleTitle |
Decreased levels of mucosal detoxification enzymes in the pouch of patients with familial adenomatous polyposis.
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pubmed:affiliation |
Department of Gastroenterology, Radboud University Medical Centre, Nijmegen, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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