Linked Life Data

16804833

Source:http://linkedlifedata.com/resource/pubmed/id/16804833

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-6-28
pubmed:abstractText
Healthcare management of the developing child with hemophilia presents several difficulties. Determining the optimum medication dose is complicated by the difficulty of performing pharmacokinetic studies in children and the fact that extrapolation from data collected in adults is generally unsatisfactory. Even when pediatric pharmacokinetic data are available, accumulating evidence suggests that there can be wide interindividual differences; age and size are important contributing factors. Achieving the venous access necessary for blood factor administration is frequently difficult in the small child. Preliminary results suggest that an arteriovenous fistula may be an appropriate option in some patients. Finally, there is the question of whether prophylactic therapy should be discontinued as patients enter adulthood. This article provides insights for managing this challenging patient population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0094-6176
pubmed:author
pubmed:issnType
Print
pubmed:volume
32 Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
28-31
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Managing the pediatric patient and the adolescent/adult transition.
pubmed:affiliation
RUSH Hemophilia and Thrombophilia Center, Chicago, IL, USA. lvalentino@rush.edu
pubmed:publicationType
Journal Article, Review