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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0005528,
umls-concept:C0014822,
umls-concept:C0030705,
umls-concept:C0031140,
umls-concept:C0439536,
umls-concept:C0441889,
umls-concept:C0442034,
umls-concept:C0871261,
umls-concept:C1280500,
umls-concept:C1515273,
umls-concept:C1516240,
umls-concept:C1704632,
umls-concept:C1705313,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:dateCreated |
1991-11-21
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pubmed:abstractText |
Anemia of CRF has been corrected by use of H-R-EPO both in hemodialysis and CAPD patients. Long term response to subcutaneous EPO and its relationship with serum EPO levels remain to be established. Twenty-five CAPD patients treated with CAPD during 30 +/- 28 (mean +/- SD) months were included in this study. The follow-up period was 6-24 months. All patients have been on CAPD at least 6 months and their Hemoglobin (Hb) level was lower than 8.5 g/dl. Twelve patients received EPO by subcutaneous route, at doses of 20 u./Kg daily and 13 other patients at doses of 2000 units twice a week. Thereafter, these doses were adjusted to obtain a Hemoglobin level ranging 10.5-13 g/dl. In conclusion, our results suggest that the subcutaneous route for H-R-Erythropoietin can be considered as the best choice for CAPD patients. Low doses twice a week seem to improve anemia in 2 months. Later, dose adjustment should be done according to the patient's response. The improvement in nutritional status we observed suggests a new positive aspect for EPO therapy. Our data did not show changes in peritoneal function.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1197-8554
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
296-300
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1680450-Adult,
pubmed-meshheading:1680450-Anemia,
pubmed-meshheading:1680450-Biological Transport,
pubmed-meshheading:1680450-Creatinine,
pubmed-meshheading:1680450-Erythropoietin,
pubmed-meshheading:1680450-Female,
pubmed-meshheading:1680450-Hematocrit,
pubmed-meshheading:1680450-Hemoglobins,
pubmed-meshheading:1680450-Humans,
pubmed-meshheading:1680450-Kidney Failure, Chronic,
pubmed-meshheading:1680450-Male,
pubmed-meshheading:1680450-Middle Aged,
pubmed-meshheading:1680450-Peritoneal Dialysis, Continuous Ambulatory,
pubmed-meshheading:1680450-Peritoneum,
pubmed-meshheading:1680450-Ultrafiltration,
pubmed-meshheading:1680450-Urea
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pubmed:year |
1991
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pubmed:articleTitle |
Medium term response to H-R erythropoietin in CAPD patients: the influence of erythropoietin plasmatic levels and the effects on peritoneal transport capacity.
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pubmed:affiliation |
Hospital La Paz, Madrid, Spain.
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pubmed:publicationType |
Journal Article
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