Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-6-28
pubmed:abstractText
CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. We demonstrate that p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0077-8923
pubmed:author
pubmed:issnType
Print
pubmed:volume
1067
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
217-9
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
CARF regulates p19ARF-p53-p21WAF1 senescence pathway by multiple checkpoints.
pubmed:affiliation
National Institute of Advanced Industrial Science & Technology (AIST), Tsukuba, Ibaraki, Japan. s-kaul@aist.go.jp
pubmed:publicationType
Journal Article, Review