Source:http://linkedlifedata.com/resource/pubmed/id/16799820
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2006-7-26
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pubmed:abstractText |
Deoxycytidine kinase (DCK) is the rate-limiting enzyme of the intracellular phosphorylation of nucleoside anticancer drugs, including gemcitabine and beta-arabinofuranosylcytosine, to their active triphosphates. This study was performed to assess the occurrence and frequency of DCK polymorphisms in a predominantly Caucasian population and to choose candidate polymorphisms for subsequent functionality studies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0031-6970
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
681-4
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pubmed:meshHeading |
pubmed-meshheading:16799820-Deoxycytidine Kinase,
pubmed-meshheading:16799820-European Continental Ancestry Group,
pubmed-meshheading:16799820-Female,
pubmed-meshheading:16799820-Genetics, Population,
pubmed-meshheading:16799820-Humans,
pubmed-meshheading:16799820-Male,
pubmed-meshheading:16799820-Polymorphism, Single Nucleotide
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pubmed:year |
2006
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pubmed:articleTitle |
Novel deoxycytidine kinase gene polymorphisms: a population screening study in Caucasian healthy volunteers.
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pubmed:affiliation |
Department of Pharmacy & Pharmacology, Slotervaart Hospital/The Netherlands Cancer Institute, Louwesweg 6, 1066 EC Amsterdam, The Netherlands. apmsj@slz.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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