Linked Life Data

16798274

Source:http://linkedlifedata.com/resource/pubmed/id/16798274

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-6-26
pubmed:abstractText
Polycystic ovary syndrome (PCOS) is associated with insulin resistance. There are also defects in pancreatic beta-cell function in affected women. These abnormalities are heritable. There are post-binding defects in insulin receptor signaling, with selective resistance to insulin's metabolic actions and constitutively activated mitogenic signaling in skeletal muscle. Intrinsic and environmental abnormalities interact to produce peripheral insulin resistance in PCOS. A susceptibility gene region for PCOS is located on chromosome 19p13.2. The susceptibility allele is also associated with a metabolic phenotype.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1556-5653
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
86 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S13-4
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Insulin resistance in women with polycystic ovary syndrome.
pubmed:affiliation
Division of Endocrinology, Metabolism and Molecular Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA. a-dunaif@northwestern.edu
pubmed:publicationType
Journal Article