Source:http://linkedlifedata.com/resource/pubmed/id/16794636
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
2006-6-23
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| pubmed:abstractText |
Photodynamic therapy (PDT) uses non-toxic photosensitizers and harmless visible light in combination with oxygen to produce cytotoxic reactive oxygen species that kill malignant cells by apoptosis and/or necrosis, shut down the tumour microvasculature and stimulate the host immune system. In contrast to surgery, radiotherapy and chemotherapy that are mostly immunosuppressive, PDT causes acute inflammation, expression of heat-shock proteins, invasion and infiltration of the tumour by leukocytes, and might increase the presentation of tumour-derived antigens to T cells.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
1474-175X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
6
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
535-45
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| pubmed:dateRevised |
2010-12-3
|
| pubmed:meshHeading |
pubmed-meshheading:16794636-Animals,
pubmed-meshheading:16794636-Combined Modality Therapy,
pubmed-meshheading:16794636-Humans,
pubmed-meshheading:16794636-Immunotherapy,
pubmed-meshheading:16794636-Inflammation,
pubmed-meshheading:16794636-Lymphocyte Activation,
pubmed-meshheading:16794636-Neoplasms,
pubmed-meshheading:16794636-Photochemotherapy,
pubmed-meshheading:16794636-T-Lymphocytes
|
| pubmed:year |
2006
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| pubmed:articleTitle |
Photodynamic therapy and anti-tumour immunity.
|
| pubmed:affiliation |
Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Review,
Research Support, N.I.H., Extramural
|