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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2006-6-23
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pubmed:abstractText |
Hematopoietic cell transplantation may offer the only cure for patients with hematological diseases. The clinical application of this therapy has been limited by toxic conditioning and lack of matched donors. Haploidentical transplantation would serve to extend the potential donor pool; however, transplantation across major histocompatibility complex barriers is often associated with severe graft-versus-host disease. Here we evaluate a novel protocol to achieve engraftment across mismatch barriers without toxic conditioning or significant posttransplant complications.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0041-1337
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pubmed:author |
pubmed-author:CameronAndrew MAM,
pubmed-author:CinaRobert ARA,
pubmed-author:ColbyChristineC,
pubmed-author:GoodrichJenniferJ,
pubmed-author:HettiarachyShehanS,
pubmed-author:HuangChristene ACA,
pubmed-author:LeePatricia WPW,
pubmed-author:NevilleDavid MDMJr,
pubmed-author:RowlandHaleyH,
pubmed-author:SpitzerThomas RTR,
pubmed-author:WikielKrzysztof JKJ
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1677-85
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pubmed:meshHeading |
pubmed-meshheading:16794534-Animals,
pubmed-meshheading:16794534-Cell Lineage,
pubmed-meshheading:16794534-Chimerism,
pubmed-meshheading:16794534-Colony-Forming Units Assay,
pubmed-meshheading:16794534-Graft vs Host Disease,
pubmed-meshheading:16794534-Granulocyte Precursor Cells,
pubmed-meshheading:16794534-Haploidy,
pubmed-meshheading:16794534-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:16794534-Lymphocyte Count,
pubmed-meshheading:16794534-Platelet Count,
pubmed-meshheading:16794534-Swine,
pubmed-meshheading:16794534-Thymus Gland,
pubmed-meshheading:16794534-Transplantation Conditioning,
pubmed-meshheading:16794534-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
Stable multilineage chimerism without graft versus host disease following nonmyeloablative haploidentical hematopoietic cell transplantation.
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pubmed:affiliation |
Transplantation Biology Research Center-Surgery, Massachusetts General Hospital, Boston, MA 02129, USA.
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pubmed:publicationType |
Journal Article
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