Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4 Suppl
pubmed:dateCreated
2006-8-9
pubmed:abstractText
Pediatric adherence to daily drug regimens has not been widely assessed in Africa where majority of HIV infected children live. Using in-depth interviews of 42 HIV-infected children taking ART and/or cotrimoxazole prophylaxis, and 42 primary caregivers, at a comprehensive HIV/AIDS clinic in Uganda, we evaluated their adherence experiences for purposes of program improvement. Daily drug regimens provided by the pediatric clinic included cotrimoxazole prophylaxis as well as ART and cotrimoxazole combined. Complete disclosure of HIV status by caregivers to children and strong parental relationships were related to good adherence. Structural factors including poverty and stigma were barriers to adherence even for children who had had complete disclosure and a supportive relationship with a parent. To ensure adherence to life-extending medications, our findings underscore the need for providers to support caregivers to disclose, provide on-going support and maintain open communication with HIV-infected children taking cotrimoxazole prophylaxis and ART.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1090-7165
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S85-93
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:16791525-AIDS-Related Opportunistic Infections, pubmed-meshheading:16791525-Adolescent, pubmed-meshheading:16791525-Adult, pubmed-meshheading:16791525-Anti-HIV Agents, pubmed-meshheading:16791525-Anti-Infective Agents, pubmed-meshheading:16791525-Antibiotic Prophylaxis, pubmed-meshheading:16791525-Caregivers, pubmed-meshheading:16791525-Child, pubmed-meshheading:16791525-Child, Preschool, pubmed-meshheading:16791525-Drug Therapy, Combination, pubmed-meshheading:16791525-HIV Infections, pubmed-meshheading:16791525-HIV Seropositivity, pubmed-meshheading:16791525-Humans, pubmed-meshheading:16791525-Interviews as Topic, pubmed-meshheading:16791525-Patient Compliance, pubmed-meshheading:16791525-Trimethoprim-Sulfamethoxazole Combination, pubmed-meshheading:16791525-Truth Disclosure, pubmed-meshheading:16791525-Uganda
pubmed:year
2006
pubmed:articleTitle
Disclosure of HIV status and adherence to daily drug regimens among HIV-infected children in Uganda.
pubmed:affiliation
CDC-Uganda, Global AIDS Program, Kampala, Uganda. wmb8@ug.cdc.gov
pubmed:publicationType
Journal Article