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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5977
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pubmed:dateCreated |
1975-11-6
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pubmed:abstractText |
Raised plasma immunoreactive corticotrophin (ACTH) levels were found in five boys with the sex-linked disorder progressive leucodystrophy associated with adrenal insufficiency (Addison-Schilder's disease) and in a symptom-free brother of one of them. Similar ACTH concentrations were found using two antisera, one against the N-terminal part of the ACTH molecule and the other against the C-terminal part. In one patient the circulating ACTH had normal biological activity as measured using the cytochemical ACTH bioassay. Immunoreactive beta/-melanocyte-stimulating hormone was also determined in one patient and found to be raised.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0007-1447
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
26
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
201-2
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:167903-17-Hydroxycorticosteroids,
pubmed-meshheading:167903-17-Ketosteroids,
pubmed-meshheading:167903-Addison Disease,
pubmed-meshheading:167903-Adrenocorticotropic Hormone,
pubmed-meshheading:167903-Child,
pubmed-meshheading:167903-Child, Preschool,
pubmed-meshheading:167903-Cosyntropin,
pubmed-meshheading:167903-Diffuse Cerebral Sclerosis of Schilder,
pubmed-meshheading:167903-Humans,
pubmed-meshheading:167903-Immune Sera,
pubmed-meshheading:167903-Male,
pubmed-meshheading:167903-Melanocyte-Stimulating Hormones,
pubmed-meshheading:167903-Sex Factors
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pubmed:year |
1975
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pubmed:articleTitle |
Plasma corticotrophin levels in addison-schilder's disease.
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pubmed:publicationType |
Journal Article
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