Source:http://linkedlifedata.com/resource/pubmed/id/16790352
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2006-7-24
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pubmed:abstractText |
We prospectively investigated the short-term effects of intravenous methyl-prednisolone (IVMP) on cerebral volume in patients suffering a multiple sclerosis (MS) relapse. Ten patients underwent MRI brain studies immediately before and after IVMP treatment, and 4 and 8 weeks later. Whole brain volumes decreased significantly over the 8-week period. The greatest change occurred during IVMP administration. This has implications for MS treatment trials using cerebral atrophy as an endpoint.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0967-5868
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
636-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16790352-Adult,
pubmed-meshheading:16790352-Anti-Inflammatory Agents,
pubmed-meshheading:16790352-Cerebral Cortex,
pubmed-meshheading:16790352-Female,
pubmed-meshheading:16790352-Humans,
pubmed-meshheading:16790352-Magnetic Resonance Imaging,
pubmed-meshheading:16790352-Male,
pubmed-meshheading:16790352-Methylprednisolone,
pubmed-meshheading:16790352-Middle Aged,
pubmed-meshheading:16790352-Multiple Sclerosis, Relapsing-Remitting,
pubmed-meshheading:16790352-Prospective Studies,
pubmed-meshheading:16790352-Time Factors
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pubmed:year |
2006
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pubmed:articleTitle |
Short-term effects of methylprednisolone on cerebral volume in multiple sclerosis relapses.
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pubmed:affiliation |
Department of Neurology, The Royal Melbourne Hospital, Parkville, Victoria 3050, Australia.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, Non-U.S. Gov't
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