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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2006-6-21
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pubmed:abstractText |
The short-chain fatty acids (SCFA) are produced via anaerobic bacterial fermentation of dietary fiber within the colonic lumen. Among them, butyrate is thought to protect against colon carcinogenesis. However, few studies analyze the effects of butyrate, and other SCFA, on normal epithelial cells and on epithelial regeneration during disease recovery. Since there are controversial in vitro studies, we have explored the effects of SCFA on different biological processes.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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|
pubmed:issn |
0171-5216
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
132
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
487-97
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pubmed:dateRevised |
2007-9-6
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pubmed:meshHeading |
pubmed-meshheading:16788843-Adenocarcinoma,
pubmed-meshheading:16788843-Alkaline Phosphatase,
pubmed-meshheading:16788843-Animals,
pubmed-meshheading:16788843-Apoptosis,
pubmed-meshheading:16788843-Blotting, Western,
pubmed-meshheading:16788843-Butyric Acid,
pubmed-meshheading:16788843-Cell Proliferation,
pubmed-meshheading:16788843-Cell Survival,
pubmed-meshheading:16788843-Colonic Neoplasms,
pubmed-meshheading:16788843-Epithelial Cells,
pubmed-meshheading:16788843-Fatty Acids, Volatile,
pubmed-meshheading:16788843-Female,
pubmed-meshheading:16788843-HT29 Cells,
pubmed-meshheading:16788843-Humans,
pubmed-meshheading:16788843-Intestinal Mucosa,
pubmed-meshheading:16788843-Phenotype,
pubmed-meshheading:16788843-Proliferating Cell Nuclear Antigen,
pubmed-meshheading:16788843-Rats,
pubmed-meshheading:16788843-Rats, Wistar
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pubmed:year |
2006
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pubmed:articleTitle |
The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype.
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pubmed:affiliation |
Department of Pharmacology, School of Pharmacy, University of Granada, Campus Universitario "La Cartuja" s/n, 18071, Granada, Spain. jxaus@puleva.es
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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