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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
16
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pubmed:dateCreated |
2006-8-10
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pubmed:abstractText |
High-density DNA tiling microarrays are a powerful tool for the characterization of complete transcriptomes. The two major analytical challenges are the segmentation of the hybridization signal along genomic coordinates to accurately determine transcript boundaries and the adjustment of the sequence-dependent response of the oligonucleotide probes to achieve quantitative comparability of the signal between different probes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1367-4811
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1963-70
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pubmed:dateRevised |
2009-11-4
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pubmed:meshHeading |
pubmed-meshheading:16787969-Algorithms,
pubmed-meshheading:16787969-Computational Biology,
pubmed-meshheading:16787969-DNA,
pubmed-meshheading:16787969-Gene Expression Profiling,
pubmed-meshheading:16787969-Genome,
pubmed-meshheading:16787969-Models, Statistical,
pubmed-meshheading:16787969-Nucleic Acid Hybridization,
pubmed-meshheading:16787969-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:16787969-Oligonucleotide Probes,
pubmed-meshheading:16787969-Oligonucleotides,
pubmed-meshheading:16787969-RNA, Messenger,
pubmed-meshheading:16787969-Saccharomyces cerevisiae,
pubmed-meshheading:16787969-Transcription, Genetic
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pubmed:year |
2006
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pubmed:articleTitle |
Transcript mapping with high-density oligonucleotide tiling arrays.
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pubmed:affiliation |
European Molecular Biology Laboratory, European Bioinformatics Institute, Cambridge CB10 1SD, UK. huber@ebi.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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