rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-7-31
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pubmed:abstractText |
A cis-isomer of a C(8)-diol ester of okadaic acid (1) was isolated during large-scale purification of pectenotoxins (PTXs) from extracts of Dinophysis acuta collected from the west coast of South Island, New Zealand. The compound was identified by NMR spectroscopic and liquid chromatography-mass spectrometry (LC-MS) studies, and is the first reported cis-isomer of an okadaic acid C(8)-diol-ester identified in Dinophysis. The more abundant trans-C(8)-diol ester of okadaic acid (2) isolated from the same Dinophysis extract was rapidly hydrolyzed to okadaic acid in vitro by the supernatant from green-lipped mussel hepatopancreas.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0041-0101
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-203
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16784765-Animals,
pubmed-meshheading:16784765-Chromatography, High Pressure Liquid,
pubmed-meshheading:16784765-Dinoflagellida,
pubmed-meshheading:16784765-Esterification,
pubmed-meshheading:16784765-Furans,
pubmed-meshheading:16784765-Hepatopancreas,
pubmed-meshheading:16784765-Hydrolysis,
pubmed-meshheading:16784765-Magnetic Resonance Spectroscopy,
pubmed-meshheading:16784765-Marine Toxins,
pubmed-meshheading:16784765-Molecular Structure,
pubmed-meshheading:16784765-Okadaic Acid,
pubmed-meshheading:16784765-Pyrans,
pubmed-meshheading:16784765-Spectrometry, Mass, Electrospray Ionization
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pubmed:year |
2006
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pubmed:articleTitle |
Isolation and identification of a cis-C8-diol-ester of okadaic acid from Dinophysis acuta in New Zealand.
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pubmed:affiliation |
AgResearch Ltd., Ruakura Research Centre, Private Bag 3123, Hamilton, New Zealand. chris.miles@agresearch.co.nz
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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