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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2006-9-4
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pubmed:abstractText |
Rosuvastatin, a novel potent HMG-CoA reductase inhibitor, is excreted into bile mediated by breast cancer resistance protein (BCRP). Our objective was to determine the association between the most frequent single nucleotide polymorphisms (SNPs) of the BCRP (421C>A) and the pharmacokinetics of rosuvastatin.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0009-8981
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pubmed:author |
pubmed-author:AnWangW,
pubmed-author:Fen-Jiang,
pubmed-author:HeYi-JingYJ,
pubmed-author:HuangYuan-FeiYF,
pubmed-author:JeuJ FJF,
pubmed-author:LiuYa-LiYL,
pubmed-author:LiuZhao-QianZQ,
pubmed-author:StamJ WJW,
pubmed-author:TanZhi-RongZR,
pubmed-author:YuBang-NingBN,
pubmed-author:ZhangWeiW,
pubmed-author:ZhouHong-HaoHH
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pubmed:issnType |
Print
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pubmed:volume |
373
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
99-103
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16784736-ATP-Binding Cassette Transporters,
pubmed-meshheading:16784736-Administration, Oral,
pubmed-meshheading:16784736-China,
pubmed-meshheading:16784736-Fluorobenzenes,
pubmed-meshheading:16784736-Genetic Testing,
pubmed-meshheading:16784736-Genotype,
pubmed-meshheading:16784736-Heterozygote,
pubmed-meshheading:16784736-Homozygote,
pubmed-meshheading:16784736-Humans,
pubmed-meshheading:16784736-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:16784736-Male,
pubmed-meshheading:16784736-Neoplasm Proteins,
pubmed-meshheading:16784736-Polymorphism, Single Nucleotide,
pubmed-meshheading:16784736-Pyrimidines,
pubmed-meshheading:16784736-Reference Values,
pubmed-meshheading:16784736-Sulfonamides
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pubmed:year |
2006
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pubmed:articleTitle |
Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males.
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pubmed:affiliation |
Pharmacogenetics Research Institute, Institute of Clinical Pharmacology, Central South University, Changsha, Hunan 410078, P.R. China.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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