Linked Life Data

16783468

Source:http://linkedlifedata.com/resource/pubmed/id/16783468

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2006-6-19
pubmed:abstractText
CGD is a rare phagocytic disorder manifesting as recurrent, severe bacterial and fungal infections. We describe an Iranian family with eight children, of whom six, five males and one female were diagnosed with CGD resulting in diffuse pulmonary sterile granulomatous lesions. Three died despite multiple courses of antibiotic and antituberculosis medications while three are alive, to date they are asymptomatic but with imaging and pathologic findings of pulmonary granulomatosis, treated with steroids. The parents are healthy. Our report describes the clinical manifestations and outcome in this family. The inheritance pattern suggests an autosomal recessive pattern with high penetrance.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0271-9142
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
291-6
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Chronic granulomatous disease with unusual clinical manifestation, outcome, and pattern of inheritance in an Iranian family.
pubmed:affiliation
National Research Institute for Tuberculosis and Lung Diseases, Masih Daneshvary Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
pubmed:publicationType
Journal Article, Case Reports