Linked Life Data

16781821

Source:http://linkedlifedata.com/resource/pubmed/id/16781821

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-7-21
pubmed:abstractText
For most of the patients with cancer comorbidity had independent prognostic effect. This negative influence of comorbidity on survival of cancer might be due to several mechanisms: the increased risk of death due to the comorbid condition itself, more contra-indications for anti-cancer treatment, more indications for dose reduction and a higher rate of treatment-related complications, such as infections and cardiovascular events. It is known that in some chronic diseases (e.g., coronary artery disease, hypertension, and obesity) pro-angiogenic growth factors are increased compared to controls and mostly normalized after specific treatment. We propose that increased pro-angiogenic growth factor levels in cancer patients due to comorbidities may lead to the progression of the tumors and poor prognosis. Treatment of comorbidities besides the treatment of primary tumor may further increase effective management of cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0306-9877
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
744-6
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Treatment of comorbidities besides the treatment of primary tumor may further increase effective management of cancer.
pubmed:affiliation
Department of Medical Oncology, Hacettepe University, Institute of Oncology, 06100 Sihhiye, Ankara, Turkey. saksoy07@yahoo.com
pubmed:publicationType
Journal Article