|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0018935,
umls-concept:C0026336,
umls-concept:C0026933,
umls-concept:C0206153,
umls-concept:C0376690,
umls-concept:C0439801,
umls-concept:C0439810,
umls-concept:C0680844,
umls-concept:C0681916,
umls-concept:C0750572,
umls-concept:C0870078,
umls-concept:C2323499
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|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2006-6-16
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|
pubmed:abstractText |
Renal transplant patients with suboptimal mycophenolic acid (MPA) areas under the curves (AUCs) are at greater risk of acute rejection. In hematopoietic cell transplantation, a low MPA AUC is also associated with a higher incidence of acute graft versus host disease. Therefore, a limited sampling model was developed and validated to simultaneously estimate total and unbound MPA AUC0-12 in hematopoietic cell transplantation patients.
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
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|
pubmed:issn |
0163-4356
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
28
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
394-401
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pubmed:dateRevised |
2007-11-14
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|
pubmed:meshHeading |
pubmed-meshheading:16778725-Administration, Oral,
pubmed-meshheading:16778725-Adult,
pubmed-meshheading:16778725-Area Under Curve,
pubmed-meshheading:16778725-Chromatography, High Pressure Liquid,
pubmed-meshheading:16778725-Cyclosporine,
pubmed-meshheading:16778725-Drug Monitoring,
pubmed-meshheading:16778725-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:16778725-Humans,
pubmed-meshheading:16778725-Immunosuppressive Agents,
pubmed-meshheading:16778725-Injections, Intravenous,
pubmed-meshheading:16778725-Models, Biological,
pubmed-meshheading:16778725-Mycophenolic Acid,
pubmed-meshheading:16778725-Reproducibility of Results,
pubmed-meshheading:16778725-Spectrophotometry, Ultraviolet
|
|
pubmed:year |
2006
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|
pubmed:articleTitle |
A limited sampling model for estimation of total and unbound mycophenolic acid (MPA) area under the curve (AUC) in hematopoietic cell transplantation (HCT).
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pubmed:affiliation |
Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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