rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
16
|
pubmed:dateCreated |
2006-7-17
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pubmed:abstractText |
The cyanobacterium Hassallia sp. produces a family of four compounds which exhibit a broad spectrum of antifungal activities. So far only one of these members has been isolated and its structure elucidated. In this study, we present a second member of this group. Mass spectrometry, one- and two-dimensional NMR and chiral GC-MS analysis revealed the same peptidic and fatty acid core for hassallidin B as the first member hassallidin A with an additional carbohydrate unit, a rhamnose attached to the 3-hydroxyl group of the C(14)-acyl side chain. The antifungal potential of hassallidin B is nearly identical to that of hassallidin A.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0960-894X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
4220-2
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16777415-Antifungal Agents,
pubmed-meshheading:16777415-Chemistry, Pharmaceutical,
pubmed-meshheading:16777415-Cyanobacteria,
pubmed-meshheading:16777415-Drug Design,
pubmed-meshheading:16777415-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:16777415-Glycolipids,
pubmed-meshheading:16777415-Glycopeptides,
pubmed-meshheading:16777415-Lipopeptides,
pubmed-meshheading:16777415-Lipoproteins,
pubmed-meshheading:16777415-Magnetic Resonance Spectroscopy,
pubmed-meshheading:16777415-Microbial Sensitivity Tests,
pubmed-meshheading:16777415-Models, Chemical,
pubmed-meshheading:16777415-Peptides, Cyclic
|
pubmed:year |
2006
|
pubmed:articleTitle |
Hassallidin B--second antifungal member of the Hassallidin family.
|
pubmed:affiliation |
Technische Universität Berlin, Fak. II, Institut für Chemie, Berlin, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|