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rdf:type |
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lifeskim:mentions |
umls-concept:C0011155,
umls-concept:C0017262,
umls-concept:C0027651,
umls-concept:C0171955,
umls-concept:C0185117,
umls-concept:C0337112,
umls-concept:C0392756,
umls-concept:C1155661,
umls-concept:C1524075,
umls-concept:C1527249,
umls-concept:C1552644,
umls-concept:C1823153,
umls-concept:C2349976,
umls-concept:C2700462,
umls-concept:C2911684
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pubmed:issue |
8
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pubmed:dateCreated |
2006-8-10
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pubmed:abstractText |
Tumor budding at the invasive margin of colorectal cancer is an important adverse prognostic factor. The subset of colorectal cancer that is deficient in DNA mismatch repair has been associated with a good prognosis. It is hypothesized that tumor budding in this subset may lack biologic aggressiveness because it is not associated with aberrant expression of the independent prognostic factor, laminin-5 gamma 2.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Proteins, Signal Transducing,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/LAMC2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Laminin,
http://linkedlifedata.com/resource/pubmed/chemical/MLH1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MSH2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MutS Homolog 2 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0012-3706
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1193-202
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16773493-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:16773493-Adult,
pubmed-meshheading:16773493-Aged,
pubmed-meshheading:16773493-Aged, 80 and over,
pubmed-meshheading:16773493-Base Pair Mismatch,
pubmed-meshheading:16773493-Carrier Proteins,
pubmed-meshheading:16773493-Chi-Square Distribution,
pubmed-meshheading:16773493-Colorectal Neoplasms,
pubmed-meshheading:16773493-Colorectal Neoplasms, Hereditary Nonpolyposis,
pubmed-meshheading:16773493-DNA Repair,
pubmed-meshheading:16773493-Female,
pubmed-meshheading:16773493-Germ-Line Mutation,
pubmed-meshheading:16773493-Humans,
pubmed-meshheading:16773493-Immunohistochemistry,
pubmed-meshheading:16773493-Laminin,
pubmed-meshheading:16773493-Male,
pubmed-meshheading:16773493-Middle Aged,
pubmed-meshheading:16773493-MutS Homolog 2 Protein,
pubmed-meshheading:16773493-Neoplasm Proteins,
pubmed-meshheading:16773493-Nuclear Proteins,
pubmed-meshheading:16773493-Proto-Oncogene Proteins
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pubmed:year |
2006
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pubmed:articleTitle |
Tumor buds show reduced expression of laminin-5 gamma 2 chain in DNA mismatch repair deficient colorectal cancer.
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pubmed:affiliation |
Department of Pathology, McGill University, Montreal, Canada. eiji-c@zf6.so-net.ne.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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