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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2006-9-8
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pubmed:abstractText |
The mechanisms responsible for the ectopic adrenal expression of glucose-dependent insulinotropic peptide (GIP) receptor (GIPR) in GIP-dependent Cushing's syndrome (CS) are unknown. Chronic adrenal stimulation by ACTH in Cushing's disease or GIP in GIP-dependent ACTH-independent macronodular adrenal hyperplasia both lead to the induction of genes implicated in adrenal proliferation and steroidogenesis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0021-972X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3611-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16772347-Adolescent,
pubmed-meshheading:16772347-Adrenal Glands,
pubmed-meshheading:16772347-Adult,
pubmed-meshheading:16772347-Cushing Syndrome,
pubmed-meshheading:16772347-Gastric Inhibitory Polypeptide,
pubmed-meshheading:16772347-Gene Expression Profiling,
pubmed-meshheading:16772347-Humans,
pubmed-meshheading:16772347-Hyperplasia,
pubmed-meshheading:16772347-Middle Aged,
pubmed-meshheading:16772347-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:16772347-RNA,
pubmed-meshheading:16772347-Receptors, Gastrointestinal Hormone,
pubmed-meshheading:16772347-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16772347-Signal Transduction
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pubmed:year |
2006
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pubmed:articleTitle |
Whole genome expression profiling of glucose-dependent insulinotropic peptide (GIP)- and adrenocorticotropin-dependent adrenal hyperplasias reveals novel targets for the study of GIP-dependent Cushing's syndrome.
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pubmed:affiliation |
Department of Medicine, Hôtel-Dieu du Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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