Linked Life Data

16770554

Source:http://linkedlifedata.com/resource/pubmed/id/16770554

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2007-3-1
pubmed:abstractText
Obesity is a growing clinical problem reaching epidemic proportions in developed and developing countries. It is associated with several comorbidities including cardiovascular diseases. There is strong evidence for the association of excess weight and established metabolic risk factors for coronary artery disease (CAD) such as hyperlipidemia, high blood pressure and type 2 diabetes. In addition, obesity may promote cardiovascular disease independent of these factors, possibly via hormones secreted by adipocytes, promotion of proinflammatory processes or other as yet unrecognized mechanisms. In this article the authors will outline the heredity of body weight and CAD/myocardial infarction and describe genetic factors involved in the etiology of these diseases. The methods commonly applied for the detection of such factors are described (e. g., animal models, linkage studies, association studies, etc.). These methods are discussed either in the paragraphs on obesity or on CAD; the described principles apply to both phenotypes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0340-9937
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-99
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Genetic factors for overweight and CAD.
pubmed:affiliation
Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, and Medical Clinic II, University Hospital Schleswig-Holstein, Campus Luebeck, Germany. guenger.broenner@uni-duisburg-essen.de
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't