Source:http://linkedlifedata.com/resource/pubmed/id/16770417
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
13
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pubmed:dateCreated |
2006-6-13
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pubmed:abstractText |
A single-cell diagnostic technique for epithelial cancers is developed by utilizing laser trapping and Raman spectroscopy to differentiate cancerous and normal epithelial cells. Single-cell suspensions were prepared from surgically removed human colorectal tissues following standard primary culture protocols and examined in a near-infrared laser-trapping Raman spectroscopy system, where living epithelial cells were investigated one by one. A diagnostic model was built on the spectral data obtained from 8 patients and validated by the data from 2 new patients. Our technique has potential applications from epithelial cancer diagnosis to the study of cell dynamics of carcinogenesis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0146-9592
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2015-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16770417-Adenocarcinoma,
pubmed-meshheading:16770417-Adult,
pubmed-meshheading:16770417-Aged,
pubmed-meshheading:16770417-Colorectal Neoplasms,
pubmed-meshheading:16770417-Diagnosis, Computer-Assisted,
pubmed-meshheading:16770417-Female,
pubmed-meshheading:16770417-Humans,
pubmed-meshheading:16770417-Intestinal Mucosa,
pubmed-meshheading:16770417-Male,
pubmed-meshheading:16770417-Middle Aged,
pubmed-meshheading:16770417-Reproducibility of Results,
pubmed-meshheading:16770417-Sensitivity and Specificity,
pubmed-meshheading:16770417-Spectrum Analysis, Raman,
pubmed-meshheading:16770417-Tumor Cells, Cultured,
pubmed-meshheading:16770417-Tumor Markers, Biological
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pubmed:year |
2006
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pubmed:articleTitle |
Diagnosis of colorectal cancer using Raman spectroscopy of laser-trapped single living epithelial cells.
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pubmed:affiliation |
Key Laboratory for Quantum Optics, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai, China. kunchen@siom.ac.cn
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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