Linked Life Data

16765297

Source:http://linkedlifedata.com/resource/pubmed/id/16765297

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2006-6-12
pubmed:abstractText
Despite advances in drug therapy, severe sustained pulmonary arterial hypertension can be a fatal disease. When medical therapy is exhausted, transplantation may be an option. The most common approaches are heart-lung transplantation or double-lung transplantation, with repair of the cardiac defect if necessary. Single-lung transplantation optimises the use of scarce donors but leads to particular management problems. Heterotopic cardiac transplantation has occasionally been employed in subjects with pulmonary vascular disease secondary to cardiac disease. Timing of transplantation is a difficult decision and depends largely on the aetiology of pulmonary arterial hypertension and the rate of decline. Outcomes following transplantation are steadily improving but remain poorer than for other solid organ transplants, mainly because of the high incidence of post-transplant bronchiolitis obliterans syndrome.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1526-0542
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
117-22
pubmed:dateRevised
2009-10-14
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Transplantation as a treatment for end-stage pulmonary hypertension in childhood.
pubmed:affiliation
Formerly Harefield Hospital, Middlesex, and Great Ormond Street Hospital for Children, London, UK.
pubmed:publicationType
Journal Article, Review