Linked Life Data

16765097

Source:http://linkedlifedata.com/resource/pubmed/id/16765097

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-7-25
pubmed:abstractText
The present study was an attempt to elucidate the effect of non-lethal arsenic (As) exposure (1/10 LC50) on different immunologically important organs and cells of a catfish. Clarias batrachus L. were exposed to arsenic trioxide for different time intervals, which resulted in significant, time-dependent changes in total head kidney and splenic leucocyte count (p<0.05) and reduction in the organosomatic indices (p<0.05) of these two important immunocompetent organs. Routine histological studies revealed arsenic induced changes in the cellular composition of head kidney and spleen. Arsenic also induced time-dependent and tissue-specific alterations in T and B cell functioning in catfish. When checked for its effects on macrophages, it was noted that arsenic interfered with bacterial phagocytosis. Furthermore, arsenic affected the general immune status of C. batrachus and rendered the fish immunocompromised and susceptible to pathogens.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1532-0456
pubmed:author
pubmed:issnType
Print
pubmed:volume
143
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
455-63
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Perturbations in the catfish immune responses by arsenic: organ and cell specific effects.
pubmed:affiliation
Immunobiology Laboratory, School of Life Sciences, Visva-Bharati University, Santiniketan 731 235, India.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't