Source:http://linkedlifedata.com/resource/pubmed/id/16763599
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2006-6-9
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pubmed:abstractText |
The number of software packages for kinetic modeling of biochemical networks continues to grow. Although most packages share a common core of functionality, the specific capabilities and user interfaces of different packages mean that choosing the best package for a given task is not trivial. We compare 12 software packages with respect to their functionality, reliability, efficiency, user-friendliness and compatibility. Although most programs performed reliably in all numerical tasks tested, SBML compatibility and the set-up of multicompartmentalization are problematic in many packages. For simple models, GEPASI seems the best choice for non-expert users. For large-scale models, environments such as Jarnac/JDesigner are preferable, because they allow modular implementation of models. Virtual Cell is the most versatile program and provides the simplest and clearest functionality for setting up multicompartmentalization.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1087-0156
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
667-72
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16763599-Biochemistry,
pubmed-meshheading:16763599-Cell Physiological Phenomena,
pubmed-meshheading:16763599-Computer Simulation,
pubmed-meshheading:16763599-Kinetics,
pubmed-meshheading:16763599-Models, Biological,
pubmed-meshheading:16763599-Programming Languages,
pubmed-meshheading:16763599-Signal Transduction,
pubmed-meshheading:16763599-Software,
pubmed-meshheading:16763599-Software Validation,
pubmed-meshheading:16763599-User-Computer Interface
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pubmed:year |
2006
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pubmed:articleTitle |
Tools for kinetic modeling of biochemical networks.
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pubmed:affiliation |
Departament Ciencies Mediques Basiques, Universidad de Lleida, Montserrat Roig, 4; 25008 Lleida, Spain. ralves@cmb.udl.es
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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