Genetic differences in the activity of phosphotyrosine phosphatases between mother and embryo could result in a differential activation of signals induced by growth factors in the two sides of placenta. Previous observations suggest that this may have important effects on intrauterine development and survival. The aim of the present study is to confirm previous observations and show new data.
Department of Biopathology and Imaging Diagnostics, School of Medicine, University of Rome Tor Vergata, via Montpellier 1, 00133 Rome, Italy. gloria@med.uniroma2.it