|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:dateCreated |
2006-6-8
|
|
pubmed:abstractText |
A retrospective clinical and a genetic study was carried out of severe subepithelial corneal haze occurring after photorefractive keratectomy (PRK). Since this clinical condition resembles the lumican-null mouse phenotype, mutation analysis of lumican and keratocan was carried out to investigate whether germline genetic alterations have an effect on development of severe corneal haze in humans. Corneal thickness, photoablation depth, and severity of persistent corneal haze were also analyzed. In vivo confocal microscopy examination was also performed to study corneal structure and endothelial cells.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1090-0535
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
12
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
597-605
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:16760896-Adult,
pubmed-meshheading:16760896-Case-Control Studies,
pubmed-meshheading:16760896-Cell Count,
pubmed-meshheading:16760896-Chondroitin Sulfate Proteoglycans,
pubmed-meshheading:16760896-Cornea,
pubmed-meshheading:16760896-Corneal Opacity,
pubmed-meshheading:16760896-Endothelium, Corneal,
pubmed-meshheading:16760896-Female,
pubmed-meshheading:16760896-Humans,
pubmed-meshheading:16760896-Keratan Sulfate,
pubmed-meshheading:16760896-Lasers, Excimer,
pubmed-meshheading:16760896-Male,
pubmed-meshheading:16760896-Microscopy, Confocal,
pubmed-meshheading:16760896-Photorefractive Keratectomy,
pubmed-meshheading:16760896-Proteoglycans,
pubmed-meshheading:16760896-Retrospective Studies,
pubmed-meshheading:16760896-Severity of Illness Index
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
The role of lumican and keratocan genes in persistent subepithelial corneal haze following excimer laser photorefractive keratectomy.
|
|
pubmed:affiliation |
Department of Ophthalmology, Semmelweis University, Faculty of Medicine, Budapest, Hungary. szabo_viktoria@hotmail.com
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
