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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2006-6-8
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pubmed:abstractText |
Aldosterone is one of the main effectors of the renin-angiotensin-aldosterone system regulating blood pressure. Previous studies have shown that the aldosterone synthase promoter polymorphism -344T/C influences aldosterone levels and is associated with hypertension, a risk factor for the initiation and progression of diabetic nephropathy. Therefore, we investigated whether the -344T/C polymorphism is associated with the development and progression of diabetic nephropathy in Type 1 diabetes mellitus.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0742-3071
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
675-80
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pubmed:meshHeading |
pubmed-meshheading:16759311-Adult,
pubmed-meshheading:16759311-Aldosterone Synthase,
pubmed-meshheading:16759311-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:16759311-Case-Control Studies,
pubmed-meshheading:16759311-Chi-Square Distribution,
pubmed-meshheading:16759311-Diabetes Mellitus, Type 1,
pubmed-meshheading:16759311-Diabetic Nephropathies,
pubmed-meshheading:16759311-Disease Progression,
pubmed-meshheading:16759311-European Continental Ancestry Group,
pubmed-meshheading:16759311-Female,
pubmed-meshheading:16759311-Follow-Up Studies,
pubmed-meshheading:16759311-Gene Frequency,
pubmed-meshheading:16759311-Glomerular Filtration Rate,
pubmed-meshheading:16759311-Humans,
pubmed-meshheading:16759311-Hypertension,
pubmed-meshheading:16759311-Male,
pubmed-meshheading:16759311-Middle Aged,
pubmed-meshheading:16759311-Polymorphism, Genetic,
pubmed-meshheading:16759311-Statistics, Nonparametric
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pubmed:year |
2006
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pubmed:articleTitle |
Aldosterone synthase (CYP11B2) -344T/C polymorphism is not associated with the initiation and progression of diabetic nephropathy in Caucasian Type 1 diabetic patients.
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pubmed:affiliation |
Steno Diabetes Center, Gentofte, Denmark. mlaj@steno.dk
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pubmed:publicationType |
Journal Article
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