rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
2006-6-7
|
pubmed:abstractText |
Organic anion transporting polypeptide 1B1 (OATP1B1) is a drug uptake transporter located at the sinusoidal membrane of hepatocytes. Our aim was to establish high-throughput genotyping assays for the major known single nucleotide polymorphisms (SNP) in the SLCO1B1 gene encoding OATP1B1 and to investigate the frequencies of SNPs and haplotypes of SLCO1B1 in a large Caucasian population.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0031-6970
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
62
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
409-15
|
pubmed:meshHeading |
pubmed-meshheading:16758257-Alleles,
pubmed-meshheading:16758257-Base Sequence,
pubmed-meshheading:16758257-DNA Primers,
pubmed-meshheading:16758257-European Continental Ancestry Group,
pubmed-meshheading:16758257-Female,
pubmed-meshheading:16758257-Finland,
pubmed-meshheading:16758257-Gene Frequency,
pubmed-meshheading:16758257-Genotype,
pubmed-meshheading:16758257-Haplotypes,
pubmed-meshheading:16758257-Humans,
pubmed-meshheading:16758257-Linkage Disequilibrium,
pubmed-meshheading:16758257-Male,
pubmed-meshheading:16758257-Organic Anion Transporters,
pubmed-meshheading:16758257-Pharmacogenetics,
pubmed-meshheading:16758257-Polymorphism, Single Nucleotide
|
pubmed:year |
2006
|
pubmed:articleTitle |
Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population.
|
pubmed:affiliation |
Department of Clinical Pharmacology, University of Helsinki and Helsinki University Central Hospital, PO Box 340, Helsinki, 00029 HUS, Finland.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|