Source:http://linkedlifedata.com/resource/pubmed/id/16758170
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
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| pubmed:dateCreated |
2006-7-13
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| pubmed:abstractText |
The production of several high value steroid drugs, used as progestational, adrenocortical, estrogenic and contraceptive agents, is mostly derived from 4-androstene-dione (AD) and 1,4 androsta-diene-3,17-dione (ADD). Three Vietnamese phytosterols mixtures named VN-1, VN-2 and VN-3, isolated from soybean oil may be efficiently converted into these key compounds by mycobacterial cells. Their general phytosterol composition was 55.39, 70.55, 70.19% for VN-1, VN-2 and VN-3, respectively. Moreover, values of campesterol, beta-sitosterol and stigmasterol were determined. After 120 h of shaking in suitable culture media and temperature, maximal yield conversion to ADD was higher than 70% and up to 64% to AD, for the various phytosterols mixtures assays. These results may be better when scaling-up such a procedure of phytosterols conversion.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Aug
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| pubmed:issn |
1367-5435
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
33
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
719-23
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| pubmed:meshHeading | |
| pubmed:year |
2006
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| pubmed:articleTitle |
A very efficient bioconversion of soybean phytosterols mixtures to androstanes by mycobacteria.
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| pubmed:affiliation |
Department of Biotechnological Processes, National Center for Science Research, PO Box 6990, Havana, Cuba. celso.perez@cnic.edu.cu
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| pubmed:publicationType |
Journal Article
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