|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2007-1-29
|
|
pubmed:abstractText |
The estrogen-related receptor alpha (ERRalpha or NR3B1) is a transcription factor from the nuclear receptor super-family, group III. The gene encoding ERRalpha (ESRRA) is located on chromosome 11q13, a region showing genetic linkage to body mass index and fat percentage. Through interaction with the peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha), ERRalpha regulates key enzymes involved in the beta-oxidation of fatty acids.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0307-0565
|
|
pubmed:author |
pubmed-author:AlbrechtsenAA,
pubmed-author:AndersenGG,
pubmed-author:Borch-JohnsenKK,
pubmed-author:EkJJ,
pubmed-author:GlümerCC,
pubmed-author:GrarupNN,
pubmed-author:HansenTT,
pubmed-author:JørgensenTT,
pubmed-author:JensenD PDP,
pubmed-author:LarsenL HLH,
pubmed-author:OvergaardJJ,
pubmed-author:PedersenOO,
pubmed-author:RoseC SCS,
pubmed-author:SparsøTT,
pubmed-author:TorekovS SSS
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
31
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
365-70
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:16755280-Aged,
pubmed-meshheading:16755280-Anthropometry,
pubmed-meshheading:16755280-Blood Glucose,
pubmed-meshheading:16755280-Body Constitution,
pubmed-meshheading:16755280-Chromosomes, Human, Pair 11,
pubmed-meshheading:16755280-DNA Mutational Analysis,
pubmed-meshheading:16755280-Diabetes Mellitus, Type 2,
pubmed-meshheading:16755280-Estrogen Receptor alpha,
pubmed-meshheading:16755280-Female,
pubmed-meshheading:16755280-Genetic Predisposition to Disease,
pubmed-meshheading:16755280-Heat-Shock Proteins,
pubmed-meshheading:16755280-Humans,
pubmed-meshheading:16755280-Insulin,
pubmed-meshheading:16755280-Linkage Disequilibrium,
pubmed-meshheading:16755280-Lipids,
pubmed-meshheading:16755280-Male,
pubmed-meshheading:16755280-Middle Aged,
pubmed-meshheading:16755280-Obesity,
pubmed-meshheading:16755280-Polymorphism, Single Nucleotide,
pubmed-meshheading:16755280-Quantitative Trait, Heritable,
pubmed-meshheading:16755280-Transcription Factors
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes.
|
|
pubmed:affiliation |
Steno Diabetes Center, Gentofte, Denmark.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
